Biomolecular machines can convert chemical energy into mechanical work with remarkably high efficiency. ‘Individuality’ often found in single-molecule analyses of biomolecules is thought to be intrinsic nature of biomolecules to attain flexible adaptation to ever-changing environment. We aim at the elucidation of molecular mechanisms of such sophisticated functions of biomolecules, by analyzing at the single-molecule level. We also aim to reconstitute ‘living’ molecular systems in bottom-up approach, by integrating single-molecule techniques and microdevice techniques. In addition to basic research, we pursuit the development of highly sensitive diagnostic assays and accurate screening methods based on our single-molecule techniques.
Affiliation: The Noji Laboratory
Extension number: 27252
Location: 6B03, Eng. Bldg. 3.